According to historians, Armenians have settled in Egypt since ancient times (4th century BC). Their number increased in the middle of the 7th century when the Arabs who had conquered Egypt did not interfere with the strengthening of the local Armenians.

The Egyptian-Armenian community was formed and flourished during the Fatimid era (969-1171), which was conditioned by the development of the Egyptian cities and the friendly policy of the Arab caliphs (khalifas) towards Christians. The number of Armenians also increased during the reign of the Mamluks.