Armenians began to settle in Cuba at the beginning of the 20th century, as a result of the Armenian Genocide, they were predominantly refugees from Western Armenia and Constantinople. During the 1920s through the 1940s, there were about 500 Armenians living in Cuba, concentrated in the cities of Havana, Las Tunas, and Villa Holguin. 

The community was led by a Diaspora union. An Armenian school as well as local branches of the Armenian Revolutionary Federation, the  Armenian Relief Committee, the Armenian Relief Society, Malatia, Tigranakert, and other patriotic unions operated in Cuba. Additionally, the Armenian Progressive Union, which was formed during the years of WW2 and contributed to the country’s fight against Fascism. 

Armenians in Cuba have been involved in various trades, including painting and shoemaking, they also engaged in small scale commercial activities, and served in government positions. Armenians introduce yogurt production in Cuba. 

The vast majority of Armenians left Cuba in the 1960s, after the Cuban Revolution. There are currently no Armenian community activities in Cuba, but there are about 80 Armenians living in Havana, Las Tunas, and other cities.